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Amyloid Light Chain Database
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1. Germline Gene Usage
All Kappa
All Lambda
All K1
IGKV1-12 / L5
IGKV1-13 / L4
IGKV1-16 / L1
IGKV1-17 / A30
IGKV1-27 / A20
IGKV1-33 / O18
IGKV1-39 / O12
IGKV1-5 / L12
IGKV1-6 / L11
IGKV1-9 / L8
IGKV1-NL1
IGKV1D-12 / L19
IGKV1D-16 / L15
IGKV1D-17 / L14
IGKV1D-33 / O8
IGKV1D-39 / 02
IGKV1D-43 / L23
IGKV1D-8 / L24
All K2
IGKV2-24 / A23
IGKV2-28 / A19
IGKV2-29 / A18
IGKV2-30 / A17
IGKV2-40 / O11
IGKV2D-26 / A5
IGKV2D-28 / A3
IGKV2D-29 / A2
IGKV2D-30 / A1
IGKV2D-40 / O1
All K3
IGKV3-11 / L6
IGKV3-15 / L2
IGKV3-20 / A27
IGKV3-NL1
IGKV3-NL2
IGKV3-NL3
IGKV3-NL4
IGKV3-NL5
IGKV3D-11 / L20
IGKV3D-15 / L16
IGKV3D-20 / A11
IGKV3D-7 / L25
All K4
IGKV4-1 / B3
All K5
All L1
IGLV1-36 / 1a
IGLV1-40 / 1e
IGLV1-44 / 1c
IGLV1-47 / 1g
IGLV1-51 / 1b
All L2
IGLV2-11 / 2e
IGLV2-14 / 2a2
IGLV2-18 / 2d
IGLV2-23 / 2b2
IGLV2-8 / 2c
All L3
IGLV3-1 / 3r
IGLV3-10 / 3p
IGLV3-12 / 3i
IGLV3-16 / 3a
IGLV3-19 / 3l
IGLV3-21 / 3h
IGLV3-22 / 3e
IGLV3-25 / 3m
IGLV3-27 / V2-19
IGLV3-9 / 3j
All L4
IGLV4-3 / 4c
IGLV4-60 / 4a
IGLV4-69 / 4b
All L5
IGLV5-37 / 5e
IGLV5-39 / 5a
IGLV5-45 / 5c
IGLV5-52 / 5b
All L6
IGLV6-57 / 6a
All L7
IGLV7-43 / 7a
IGLV7-46 / 7b
All L10
IGLV10-54 / 10a
OR
All Kappa
All Lambda
All K1
IGKV1-12 / L5
IGKV1-13 / L4
IGKV1-16 / L1
IGKV1-17 / A30
IGKV1-27 / A20
IGKV1-33 / O18
IGKV1-39 / O12
IGKV1-5 / L12
IGKV1-6 / L11
IGKV1-9 / L8
IGKV1-NL1
IGKV1D-12 / L19
IGKV1D-16 / L15
IGKV1D-17 / L14
IGKV1D-33 / O8
IGKV1D-39 / 02
IGKV1D-43 / L23
IGKV1D-8 / L24
All K2
IGKV2-24 / A23
IGKV2-28 / A19
IGKV2-29 / A18
IGKV2-30 / A17
IGKV2-40 / O11
IGKV2D-26 / A5
IGKV2D-28 / A3
IGKV2D-29 / A2
IGKV2D-30 / A1
IGKV2D-40 / O1
All K3
IGKV3-11 / L6
IGKV3-15 / L2
IGKV3-20 / A27
IGKV3-NL1
IGKV3-NL2
IGKV3-NL3
IGKV3-NL4
IGKV3-NL5
IGKV3D-11 / L20
IGKV3D-15 / L16
IGKV3D-20 / A11
IGKV3D-7 / L25
All K4
IGKV4-1 / B3
All K5
All L1
IGLV1-36 / 1a
IGLV1-40 / 1e
IGLV1-44 / 1c
IGLV1-47 / 1g
IGLV1-51 / 1b
All L2
IGLV2-11 / 2e
IGLV2-14 / 2a2
IGLV2-18 / 2d
IGLV2-23 / 2b2
IGLV2-8 / 2c
All L3
IGLV3-1 / 3r
IGLV3-10 / 3p
IGLV3-12 / 3i
IGLV3-16 / 3a
IGLV3-19 / 3l
IGLV3-21 / 3h
IGLV3-22 / 3e
IGLV3-25 / 3m
IGLV3-27 / V2-19
IGLV3-9 / 3j
All L4
IGLV4-3 / 4c
IGLV4-60 / 4a
IGLV4-69 / 4b
All L5
IGLV5-37 / 5e
IGLV5-39 / 5a
IGLV5-45 / 5c
IGLV5-52 / 5b
All L6
IGLV6-57 / 6a
All L7
IGLV7-43 / 7a
IGLV7-46 / 7b
All L10
IGLV10-54 / 10a
2. Clinical Category
(see
Abbreviations
)
PCD
plasma cell dyscrasia
AL
light chain amyloidosis
MM
multiple myeloma
LCDD
light chain deposition disease
WM
Waldenstrom macroglobulinemia
POEMS
POEMS syndrome
All AL-PCD
AL
AL/MM
All Other-PCD
MM
LCDD
WM
POEMS
All Non-PCD
Normal Repertoire
B Cell Malignancy
Anti-Infectious
Autoantibody
Unclassified
OR
All AL-PCD
AL
AL/MM
All Other-PCD
MM
LCDD
WM
POEMS
All Non-PCD
Normal Repertoire
B Cell Malignancy
Anti-Infectious
Autoantibody
Unclassified
3. Sample Sources
Molecule Type =
genomic DNA
mRNA
na
protein
Tissue Type =
bone marrow
bone marrow tumor
na
peripheral blood
unclassified
Cell Type =
B cell
na
plasma cell
unclassified
unknown
Or, search for any term, such as Accession Number or Patient ID.
1. Terms